SCHEMBL1011371

SCHEMBL1011371

CC(C)COC(O)Nc1nc(N)nc(N)n1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 8/20 0.33
ADRA1D P25100 3/20 0.33
ADRA1A P35348 3/20 0.33
ADRA1B P35368 3/20 0.33
HTR2C P28335 1/20 0.33
HTR6 P50406 1/20 0.33
CDK1 P06493 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
TPH1 P17752 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9014254 0.82 MEN1 (0.34) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL9197534 0.79 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL10942115 0.78 HTR7 (0.32) HTR7ADRA1DADRA1AADRA1BCDK1
SCHEMBL8468941 0.77 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BCDK1
SCHEMBL195696 0.77 HTR7 (0.34) HTR7ADRA1DADRA1AADRA1BCDK1
SCHEMBL736035 0.76 LMNA (0.31) HTR7ADRA1DADRA1AADRA1B
SCHEMBL6723863 0.73 KMT2A (0.36) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL30147276 0.72 GAA (0.36) HTR7ADRA1DADRA1AADRA1BHTR2C
SCHEMBL4455618 0.71 PRKD3 (0.36) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL25996850 0.71 HTR7 (0.35) HTR7ADRA1DADRA1AADRA1BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559620-B2 Curable coating compositions PPG INDUSTRIES OHIO, INC. (US) 2026-02-24 US disclosed
US-20230272209-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2023-08-31 US disclosed
US-20220177754-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2022-06-09 US disclosed
WO-2022010972-A1 CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2022-01-13 WO disclosed
US-9631045-B2 Polycarbodiimides having onium salt groups PPG INDUSTRIES OHIO, INC. (US) 2017-04-25 US disclosed
US-8981005-B2 Coating compositions that include onium salt group containing polycarbodiimides PPG INDUSTRIES OHIO, INC. (US) 2015-03-17 US disclosed
CN-102015804-B Polycarbodiimide PPG IND OHIO INC 2013-09-04 CN disclosed
EP-2274353-B1 POLYCARBODIIMIDES PPG IND OHIO INC (US) 2013-08-14 EP disclosed
US-20130122765-A1 POLYCARBODIIMIDES PPG INDUSTRIES OHIO, INC. (US) 2013-05-16 US disclosed
EP-2542601-A1 ONE-COMPONENT, AMBIENT CURABLE WATERBORNE COATING COMPOSITIONS, RELATED METHODS AND COATED SUBSTRATES PPG Industries Ohio, Inc. (US) 2013-01-09 EP disclosed
US-6248819-B1 POLYCARBODIIMIDE NIPPON PAINT CO., LTD. (JP) 2001-06-19 US disclosed
EP-0973834-A1 POWDER COATING COMPOSITION CONTAINING LAMELLAR PIGMENT AND RESIN ENGELHARD CORPORATION (US) 2000-01-26 EP disclosed
WO-1998046682-A1 POWDER COATING COMPOSITION CONTAINING LAMELLAR PIGMENT AND RESIN ENGELHARD CORPORATION (US) 1998-10-22 WO disclosed
US-5824144-A Powder coating composition and method ENGELHARD CORPORATION (US) 1998-10-20 US disclosed
EP-0601378-B1 Mica-containing pigment composition NIPPON PAINT CO LTD (JP) 1997-04-16 EP disclosed
US-5378275-A Melamine resin, glossy steel finish, automobiles NIPPON PAINT CO., LTD. (JP) 1995-01-03 US disclosed
EP-0601378-A1 Mica-containing pigment composition Nippon Paint Co., Ltd. (JP) 1994-06-15 EP disclosed
EP-0393579-B1 WATER BORNE METALLIC COATING COMPOSITION NIPPON PAINT CO., LTD. (JP) 1993-09-01 EP disclosed
US-5039343-A Water borne metallic coating composition NIPPON PAINT CO., LTD. (JP) 1991-08-13 US disclosed
EP-0393579-A1 Water borne metallic coating composition NIPPON PAINT CO., LTD. (JP) 1990-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559620-B2 Curable coating compositions ESD, EPHX2, EED HTR7 2935/4885ADRA1D 4217/4885ADRA1A 3801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.