Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793450 | 0.86 | MAOA (0.44) | MAOAMAOBMAPTTDP1HDAC3 | |
| SCHEMBL5961115 | 0.83 | MAOA (0.47) | MAOAMAOBMAPTTDP1HDAC3 | |
| SCHEMBL7364154 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTABCC4SMN1; SMN2 | |
| SCHEMBL6535041 | 0.80 | MAOA (0.44) | MAOAMAOBTDP1GAAMEN1 | |
| SCHEMBL25207862 | 0.79 | TDP1 (0.49) | MAOAMAOBTDP1GAAMEN1 | |
| SCHEMBL9891443 | 0.79 | MAOA (0.46) | MAOAMAOBTDP1RECQLHDAC8 | |
| SCHEMBL1566844 | 0.79 | MAOA (0.46) | ALDH1A1MAOAMAOBTDP1GAA | |
| SCHEMBL13538038 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAMAOAMAOBMAPT | |
| SCHEMBL2710714 | 0.79 | KDM4E (0.36) | ALDH1A1LMNAMAOAMAOBSMN1; SMN2 | |
| SCHEMBL14984822 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTABCC4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539104-A | 1,4 Diazocines as fibrinogen antagonists | SMITHKLINE BEECHAM CORP. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0610432-A1 | C8-CYCLIC PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009133-A1 | C8-CYCLIC PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |