Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961115 | 0.96 | MAOA (0.47) | MAOAMAOBTDP1TSHRMEN1 | |
| SCHEMBL7360782 | 0.86 | ALDH1A1 (0.46) | MAOAMAOBTDP1TSHRMEN1 | |
| SCHEMBL6535041 | 0.82 | MAOA (0.44) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL25207862 | 0.81 | TDP1 (0.49) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL9891443 | 0.81 | MAOA (0.46) | MAOAMAOBTDP1TSHRMEN1 | |
| SCHEMBL1566844 | 0.81 | MAOA (0.46) | MAOAMAOBTDP1TSHRMEN1 | |
| SCHEMBL9612246 | 0.81 | MAOA (0.43) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL5961023 | 0.80 | MAOA (0.45) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL4907521 | 0.80 | MAOA (0.45) | MAOAMAOBTDP1TSHRMEN1 | |
| SCHEMBL3297917 | 0.80 | MAOA (0.49) | MAOAMAOBTDP1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060115848-A1 | Nucleic acid end-labeling reagents | BLOKHIN ANDREI | 2006-06-01 | — | — | US | disclosed |
| US-RE39088-E1 | Amide compounds and use of the same | JAPAN TOBACCO, INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| WO-2006014588-A2 | NUCLEIC ACID END-LABELING REAGENTS | MIRUS BIO CORPORATION (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060008830-A1 | Nucleic acid end-labeling reagents | SLATTUM PAUL M | 2006-01-12 | — | — | US | disclosed |
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-1304322-A2 | Carboxylic acid compound and use thereof | Japan Tobacco Inc. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6420561-B1 | Amide compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2002-07-16 | — | — | US | disclosed |
| US-6174887-B1 | Amide compounds and use of the same | JAPAN TOBACCO INC. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060115848-A1 | Nucleic acid end-labeling reagents | POLM, POLN, POLRMT | MAOA 2278/4885MAOB 1806/4885TDP1 90/4885 |
| US-20060008830-A1 | Nucleic acid end-labeling reagents | POLM, POLN, POLRMT | MAOA 2278/4885MAOB 1806/4885TDP1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.