Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6782851 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL21847060 | 0.77 | MAOA (0.50) | MAPTMEN1KMT2AGAAATM | |
| SCHEMBL9534932 | 0.77 | MAOA (0.41) | MAPTMEN1KMT2AATMMAOA | |
| SCHEMBL14047016 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7113968 | 0.77 | MAOA (0.50) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL15047842 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8080906 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL10531163 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL6776863 | 0.76 | MAOA (0.39) | MAPTMEN1KMT2AATMMAOA | |
| SCHEMBL12200287 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1434485-B1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES | MERIAL LTD (US) | 2007-05-16 | — | — | EP | disclosed |
| US-6037365-A | ANTIINFLAMMATORY AND ANTIMETASTASIS AGENTS; CARDIOVASCULAR DISORDERS, ARTERIOSCLEROSIS | G.D. SEARLE & CO. (US) | 2000-03-14 | — | — | US | disclosed |
| US-5441974-A | Phenyl amidines lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1993012103-A1 | PHENYL AMIDINES LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |