Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177926 | 0.77 | MAOA (0.41) | MAOAMAOBNISCHATMCYP2C9 | |
| SCHEMBL7360792 | 0.77 | ALDH1A1 (0.43) | MAOAMAOBATMCYP2C9MEN1 | |
| SCHEMBL21847060 | 0.77 | MAOA (0.50) | MAOAMAOBNISCHATMCYP2C9 | |
| Hydrochloric Acid SCHEMBL6776863 | 0.76 | MAOA (0.39) | MAOAMAOBNISCHATMCYP2C9 | |
| Hydrochloric Acid SCHEMBL6782851 | 0.76 | ALDH1A1 (0.42) | MAOAMAOBATMCYP2C9MEN1 | |
| SCHEMBL15946158 | 0.74 | ALDH1A1 (0.44) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL29413779 | 0.68 | MAOA (0.58) | MAOAMAOBNISCHATMCYP2C9 | |
| SCHEMBL88261 | 0.68 | MAOA (0.58) | MAOAMAOBNISCHATMCYP2C9 | |
| SCHEMBL21077530 | 0.67 | ATM (0.38) | MAOAMAOBNISCHATMCYP2C9 | |
| SCHEMBL507362 | 0.67 | LTB4R (0.43) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540690-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-05-12 | — | — | EP | claimed |
| EP-0540690-A4 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-02-12 | — | — | EP | claimed |
| WO-1992001959-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1992-02-06 | — | — | WO | claimed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |