Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | MMP3 | P08254 | 4/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357186 | 0.80 | NPC1 (0.37) | MMP2MMP3BCHEREN | |
| SCHEMBL7395360 | 0.80 | NPC1 (0.37) | MMP2MMP3BCHEREN | |
| SCHEMBL9240630 | 0.80 | NPC1 (0.37) | MMP2MMP3BCHEREN | |
| SCHEMBL5394987 | 0.80 | PSEN1 (0.40) | MMP2MMP3BCHE | |
| SCHEMBL7360777 | 0.78 | HTT (0.44) | BCHE | |
| SCHEMBL7360787 | 0.78 | HTT (0.44) | BCHE | |
| SCHEMBL8882496 | 0.77 | PSEN1 (0.38) | MMP2MMP3LAP3ANPEPRNPEP | |
| SCHEMBL7318484 | 0.75 | LAP3 (0.49) | MMP2MMP3LAP3ANPEPRNPEP | |
| SCHEMBL8729353 | 0.71 | MMP2 (0.37) | MMP2MMP3MMP1 | |
| SCHEMBL5412730 | 0.69 | PSEN1 (0.42) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |