Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | MASP2 | O00187 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 2/20 | 0.41 |
| ▸ | KLK8 | O60259 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350811 | 0.89 | SMN1; SMN2 (0.45) | HDAC3HDAC1HDAC2NCOR2SYK | |
| SCHEMBL7944753 | 0.85 | BACE1 (0.46) | HDAC3HDAC1HDAC2NCOR2SYK | |
| SCHEMBL30386744 | 0.84 | ITGA4 (0.41) | HDAC3HDAC1HDAC2NCOR2SYK | |
| SCHEMBL27545723 | 0.83 | SMN1; SMN2 (0.49) | SYKSMN1; SMN2MASP2PPARAPPARG | |
| SCHEMBL25054127 | 0.82 | SYK (0.55) | HDAC3HDAC1HDAC2SYKMASP2 | |
| SCHEMBL8269064 | 0.80 | SYK (0.52) | HDAC3HDAC1HDAC2SYKMASP2 | |
| SCHEMBL23511587 | 0.79 | RAB9A (0.51) | SMN1; SMN2MASP2PPARAPPARGMEN1 | |
| SCHEMBL7296828 | 0.79 | ACE (0.58) | PPARAPPARG | |
| SCHEMBL14161303 | 0.79 | MAPT (0.54) | SMN1; SMN2MASP2PPARAPPARGLMNA | |
| SCHEMBL5846695 | 0.79 | HDAC1 (0.43) | HDAC3HDAC1HDAC2NCOR2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228854-B1 | 1-BENZAZEPINE DERIVATIVE ANTICOAGULANTS; STROKE PREVENTION | COR THERAPEUTICS, INC. | 2001-05-08 | — | — | US | disclosed |
| EP-0994894-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007731-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |