Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.41 |
| ▸ | FEN1 | P39748 | 8/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361732 | 0.93 | F10 (0.46) | MEN1ALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL8019690 | 0.79 | F10 (0.57) | MEN1ALDH1A1POLBKMT2AF10 | |
| SCHEMBL8031102 | 0.77 | F10 (0.57) | MEN1ALDH1A1POLBKMT2AF10 | |
| SCHEMBL7365672 | 0.75 | RAB9A (0.43) | ALDH1A1TDP1F10F2PRSS1 | |
| SCHEMBL4433962 | 0.74 | ALOX5AP (0.51) | ALOX5APFEN1 | |
| SCHEMBL8019753 | 0.73 | F10 (0.66) | F10F2PRSS1 | |
| SCHEMBL6165511 | 0.73 | F10 (0.46) | ALDH1A1POLBF10PRSS1ALOX5AP | |
| SCHEMBL7363666 | 0.73 | F10 (0.42) | KMT2AF10PRSS1ALOX5APFEN1 | |
| SCHEMBL7480433 | 0.71 | LMNA (0.44) | MEN1ALDH1A1KMT2AF10PRSS1 | |
| SCHEMBL7084412 | 0.71 | F10 (0.45) | MEN1ALDH1A1KMT2AF10ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |