Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 4/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.41 |
| ▸ | FEN1 | P39748 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031102 | 0.93 | F10 (0.57) | F10F2PRSS1SMN1; SMN2HTT | |
| SCHEMBL7361733 | 0.79 | MEN1 (0.44) | F10F2PRSS1ALOX5APFEN1 | |
| SCHEMBL7361732 | 0.75 | F10 (0.46) | F10F2PRSS1SMN1; SMN2HTT | |
| SCHEMBL7480433 | 0.73 | LMNA (0.44) | F10PRSS1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL8019749 | 0.73 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL6165511 | 0.73 | F10 (0.46) | F10PRSS1ALOX5APFEN1NAMPT | |
| SCHEMBL6166616 | 0.71 | F10 (0.52) | F10PRSS1HTTALOX5APFEN1 | |
| SCHEMBL7084412 | 0.71 | F10 (0.45) | F10ALOX5APFEN1KMT2ANAMPT | |
| SCHEMBL7061589 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2HTTALOX5APFEN1KMT2A | |
| SCHEMBL7057459 | 0.70 | RORC (0.44) | F10ALOX5APFEN1LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |