Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CEPT1 | Q9Y6K0 | 4/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089227 | 0.79 | RORC (0.45) | LMNACYP19A1 | |
| SCHEMBL7057459 | 0.75 | RORC (0.44) | LMNAF10 | |
| SCHEMBL8031102 | 0.73 | F10 (0.57) | LMNAALDH1A1F10PRSS1RAB9A | |
| SCHEMBL8019690 | 0.73 | F10 (0.57) | LMNAALDH1A1F10PRSS1RAB9A | |
| SCHEMBL7086229 | 0.73 | KMT2A (0.55) | LMNAALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL6165511 | 0.72 | F10 (0.46) | ALDH1A1F10PRSS1MAPT | |
| SCHEMBL7475555 | 0.72 | F10 (0.82) | F10PRSS1 | |
| SCHEMBL7361732 | 0.71 | F10 (0.46) | LMNAALDH1A1F10PRSS1MAPT | |
| SCHEMBL7361733 | 0.71 | MEN1 (0.44) | ALDH1A1F10PRSS1CETPMEN1 | |
| SCHEMBL7477463 | 0.71 | MRGPRX4 (0.52) | ALDH1A1PTGDR2MAPTKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |