Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972945 | 0.86 | PARP1 (0.49) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7351854 | 0.85 | PARP1 (0.48) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9559006 | 0.79 | KCNQ3 (0.44) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9559013 | 0.77 | GAA (0.44) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL19420106 | 0.77 | HTT (0.72) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7824367 | 0.77 | RAB9A (0.72) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9559008 | 0.77 | KCNQ3 (0.42) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL3917111 | 0.76 | RAB9A (1.00) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7823539 | 0.76 | MAPT (1.00) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7361739 | 0.75 | CYP2C19 (0.67) | RAB9AHTTKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550159-A | Peptide mimics useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5453440-A | Amidine functional group on benzene ring, anticoagulants | G. D. SEARLE & CO. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1993018058-A1 | PEPTIDES MIMICS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-09-16 | — | — | WO | disclosed |