⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368938 | 0.79 | KMT2A (0.30) | — | |
| SCHEMBL7359421 | 0.72 | PDE5A (0.42) | — | |
| SCHEMBL7450974 | 0.70 | PDE5A (0.45) | — | |
| SCHEMBL7365582 | 0.69 | PDE5A (0.46) | — | |
| SCHEMBL7449440 | 0.69 | PDE5A (0.56) | — | |
| SCHEMBL5078828 | 0.69 | PDE5A (0.33) | — | |
| SCHEMBL670338 | 0.67 | PDE5A (0.36) | — | |
| SCHEMBL5201813 | 0.67 | NPSR1 (0.41) | — | |
| SCHEMBL6621801 | 0.66 | PDE5A (0.62) | — | |
| SCHEMBL5198403 | 0.64 | PDE5A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001003644-A9 | PYRAZOLOPYRIMIDINONE DERIVATIVES CONJUGATED TO THIOPHENE MOIETIES OR BENZO [FUSED] 5-MEMBERED HETEROCYCLES FOR ERECTILE DYSFUNCTION | PICOWER INST MED RES (US) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001003644-A2 | PYRAZOLOPYRIMIDINONE DERIVATIVES CONJUGATED TO THIOPHENE MOIETIES OR BENZO [FUSED] 5-MEMBERED HETEROCYCLES FOR ERECTILE DYSFUNCTION | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 2001-01-18 | — | — | WO | disclosed |