Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643125 | 0.80 | LTA4H (0.60) | LTA4HMAOBPPARGALOX5SIGMAR1 | |
| SCHEMBL11440388 | 0.77 | MAOB (0.60) | LTA4HMAOBPPARGLAP3SIGMAR1 | |
| SCHEMBL357349 | 0.77 | MAOB (0.57) | LTA4HMAOBPPARGLAP3SIGMAR1 | |
| SCHEMBL360368 | 0.77 | MAOB (0.57) | LTA4HMAOBPPARGLAP3SIGMAR1 | |
| SCHEMBL758429 | 0.76 | CYSLTR2 (0.67) | LTA4HMAOBPPARGALOX5PPARA | |
| SCHEMBL8688015 | 0.74 | SIGMAR1 (0.56) | LTA4HMAOBPPARGALOX5SIGMAR1 | |
| SCHEMBL7353511 | 0.74 | LTA4H (0.56) | LTA4HPPARGALOX5LAP3SIGMAR1 | |
| Hydrazine SCHEMBL7038883 | 0.73 | ALOX5 (0.49) | LTA4HMAOBALOX5 | |
| SCHEMBL9637755 | 0.73 | MAOB (0.59) | LTA4HMAOBPPARGALOX5LAP3 | |
| SCHEMBL2750285 | 0.73 | LTA4H (0.67) | LTA4HMAOBLAP3SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |