SCHEMBL7361910

SCHEMBL7361910

NC(=O)C(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.66
HSD17B10 Q99714 4/20 0.66
HIF1A Q16665 3/20 0.66
KDM4E B2RXH2 3/20 0.66
ALDH1A1 P00352 3/20 0.66
LMNA P02545 2/20 0.66
HPGD P15428 2/20 0.66
BLM P54132 2/20 0.66
PTGS1 P23219 2/20 0.66
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
CA7 P43166 1/20 0.56
CA14 Q9ULX7 1/20 0.56
APP P05067 1/20 0.55
TP53 P04637 2/20 0.54
ALOX15 P16050 2/20 0.54
MAPK1 P28482 2/20 0.54
THPO P40225 2/20 0.54
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109163 0.90 MAPT (0.74) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL2746002 0.88 MAPT (0.68) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL5500828 0.86 MAPT (0.70) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL7105545 0.82 MAPT (0.74) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL400288 0.82 MAPT (0.73) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL30446328 0.82 MAPT (0.73) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL6420228 0.81 MAPT (0.72) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL28976197 0.80 MAPT (0.66) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL30252290 0.80 MAPT (0.66) MAPTHSD17B10HIF1AKDM4EALDH1A1
SCHEMBL7359403 0.80 NOX4 (0.47) MAPTHSD17B10HIF1AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538384-A4 OXAMIDES SMITHKLINE BEECHAM CORP (US) 1995-04-12 EP disclosed
US-5393788-A Phenylalkyl oxamides SMITHKLINE BEECHAM CORPORATION (US) 1995-02-28 US disclosed
EP-0538384-A1 OXAMIDES SMITHKLINE BEECHAM CORPORATION (US) 1993-04-28 EP disclosed
WO-1992000968-A1 OXAMIDES SMITHKLINE BEECHAM CORPORATION (US) 1992-01-23 WO disclosed