Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293476 | 0.90 | TNKS2 (0.41) | IMPDH2IMPDH1ALOX5CA2CA4 | |
| SCHEMBL7323576 | 0.88 | ALOX5 (0.38) | IMPDH2IMPDH1ALOX5TDP1TNKS2 | |
| SCHEMBL7413599 | 0.86 | ALOX5 (0.41) | IMPDH2IMPDH1ALOX5TDP1TNKS2 | |
| SCHEMBL1241214 | 0.86 | ALOX5 (0.41) | IMPDH2IMPDH1ALOX5TDP1TNKS2 | |
| SCHEMBL7325280 | 0.86 | ALOX5 (0.41) | IMPDH2IMPDH1ALOX5TDP1TNKS2 | |
| SCHEMBL13359764 | 0.83 | ALOX5 (0.40) | IMPDH2IMPDH1ALOX5TDP1IGF1R | |
| SCHEMBL17431561 | 0.80 | IMPDH2 (0.37) | IMPDH2IMPDH1ALOX5CA2CA4 | |
| SCHEMBL27633903 | 0.80 | ALOX5 (0.53) | ALOX5TDP1 | |
| SCHEMBL23909143 | 0.79 | ALOX5 (0.37) | IMPDH2IMPDH1ALOX5 | |
| SCHEMBL23888077 | 0.79 | ALOX5 (0.55) | ALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |