Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413599 | 0.98 | ALOX5 (0.41) | ALOX5IMPDH1IMPDH2LMNAPGR | |
| SCHEMBL7325280 | 0.98 | ALOX5 (0.41) | ALOX5IMPDH1IMPDH2LMNAPGR | |
| SCHEMBL1241214 | 0.98 | ALOX5 (0.41) | ALOX5IMPDH1IMPDH2LMNAPGR | |
| SCHEMBL8293476 | 0.94 | TNKS2 (0.41) | ALOX5IMPDH1IMPDH2LMNAPGR | |
| SCHEMBL7361916 | 0.88 | IMPDH2 (0.46) | ALOX5IMPDH1IMPDH2TDP1TNKS2 | |
| SCHEMBL27633903 | 0.85 | ALOX5 (0.53) | ALOX5MAPTTDP1 | |
| SCHEMBL23909143 | 0.83 | ALOX5 (0.37) | ALOX5IMPDH1IMPDH2 | |
| SCHEMBL26969207 | 0.83 | ALOX5 (0.55) | ALOX5MAPTTDP1 | |
| SCHEMBL23888077 | 0.83 | ALOX5 (0.55) | ALOX5MAPTTDP1 | |
| SCHEMBL23903704 | 0.81 | ALOX5 (0.40) | ALOX5IMPDH1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |