Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876703 | 1.00 | FPR2 (0.48) | FPR2PPARACTSSPPARGKLK7 | |
| SCHEMBL7321491 | 0.84 | PPARA (0.43) | PPARACTSSPPARGKLK5 | |
| SCHEMBL10522492 | 0.83 | KLK5 (0.46) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL7369995 | 0.75 | CTSK (0.40) | CTSSLMNAMAPT | |
| SCHEMBL7421623 | 0.75 | OPRD1 (0.38) | FPR2PPARACTSSMAPT | |
| SCHEMBL16391249 | 0.74 | FPR2 (0.47) | FPR2LMNATSHRMAPT | |
| SCHEMBL7357006 | 0.73 | MAPT (0.40) | LMNATSHRMAPT | |
| SCHEMBL7412044 | 0.73 | MAPT (0.49) | CTSSATMMAPT | |
| SCHEMBL9206954 | 0.73 | PPARA (0.36) | FPR2PPARACTSSPPARGMAPT | |
| SCHEMBL9271702 | 0.72 | MAPT (0.37) | CTSSLMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748313-A4 | CYTOKINE INHIBITING IMIDAZOLE SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORP (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0748313-A1 | CYTOKINE INHIBITING IMIDAZOLE SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023790-A1 | CYTOKINE INHIBITING IMIDAZOLE SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-08 | — | — | WO | disclosed |