Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NMBR | P28336 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363926 | 0.91 | L3MBTL1 (0.47) | KMT2ANMBR | |
| SCHEMBL7358942 | 0.85 | KMT2A (0.53) | CTSLCTSSCTSKKMT2ABRS3 | |
| SCHEMBL7356622 | 0.85 | KMT2A (0.43) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL7361056 | 0.85 | BRS3 (0.47) | CTSLCTSSKMT2ANMBRBRS3 | |
| SCHEMBL7362797 | 0.85 | SRC (0.47) | KMT2A | |
| SCHEMBL7358003 | 0.85 | KMT2A (0.55) | CTSLCTSSCTSKKMT2A | |
| SCHEMBL7364449 | 0.84 | CHRNB2 (0.47) | KMT2A | |
| SCHEMBL7358956 | 0.84 | KMT2A (0.51) | KMT2ANMBRBRS3 | |
| SCHEMBL13073498 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKNMBR | |
| SCHEMBL7764124 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKNMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |