Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278542 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL11278545 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL5166130 | 0.73 | MEN1 (0.40) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL5166135 | 0.73 | MEN1 (0.40) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL1229938 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1229940 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9651833 | 0.71 | PTGS1 (0.39) | KDM4EFDPSENPP2 | |
| SCHEMBL9869836 | 0.71 | PTGS1 (0.39) | KDM4EFDPSENPP2 | |
| SCHEMBL15561117 | 0.71 | CYP3A4 (0.39) | KDM4EALDH1A1MAPTMEN1TP53 | |
| SCHEMBL15561120 | 0.71 | CYP3A4 (0.39) | KDM4EALDH1A1MAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012697-A9 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2000-08-24 | — | — | WO | disclosed |