Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790782 | 0.86 | CHRM1 (0.47) | CHRM1HTR2CKDM4EALDH1A1PPARG | |
| SCHEMBL21370527 | 0.79 | ALDH1A1 (0.43) | CHRM1ALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL25835992 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PPARGPPARASMN1; SMN2TMEM97 | |
| SCHEMBL7357679 | 0.77 | GLA (0.40) | HTR2CKDM4EALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL25836000 | 0.77 | PPARG (0.43) | CHRM1HTR2CALDH1A1PPARGPPARA | |
| SCHEMBL24251635 | 0.75 | ALDH1A1 (0.59) | ALDH1A1PPARGPPARASMN1; SMN2MAPK1 | |
| SCHEMBL22280532 | 0.75 | LTA4H (0.48) | CHRM1KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL23027037 | 0.75 | LTA4H (0.48) | CHRM1KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL24943926 | 0.75 | KDM4E (0.50) | HTR2CKDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL1127697 | 0.74 | PPARG (0.58) | HTR2CALDH1A1PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |