Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362472 | 0.86 | CHRM1 (0.45) | CHRM1PPARGPPARAHTR2CKDM4E | |
| SCHEMBL8790348 | 0.79 | ACE2 (0.39) | HTR2CSLC15A1ACE2PREPKDM4E | |
| SCHEMBL25835992 | 0.78 | ALDH1A1 (0.42) | PPARGPPARAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL25836000 | 0.77 | PPARG (0.43) | CHRM1PPARGPPARAHTR2CALDH1A1 | |
| SCHEMBL22624509 | 0.76 | SLC15A1 (0.49) | HTR2CSLC15A1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL24251635 | 0.74 | ALDH1A1 (0.59) | PPARGPPARAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL24943926 | 0.74 | KDM4E (0.50) | HTR2CKDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL1127697 | 0.74 | PPARG (0.58) | PPARGPPARAHTR2CALDH1A1SMN1; SMN2 | |
| SCHEMBL27623292 | 0.73 | CHRM1 (0.51) | CHRM1PPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL23027037 | 0.72 | LTA4H (0.48) | CHRM1KDM4EALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |