Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276106 | 0.84 | GSK3B (0.47) | GSK3BPOLBSLC6A1PTGS1PDE4A | |
| SCHEMBL23145052 | 0.82 | GSK3B (0.46) | GSK3BPOLBSLC6A1PTGS1PDE4A | |
| SCHEMBL7362633 | 0.79 | SLC6A1 (0.45) | SLC6A1PTGS1PDE4A | |
| SCHEMBL21653995 | 0.72 | POLB (0.43) | GSK3BPOLB | |
| SCHEMBL3271181 | 0.72 | PKM (0.48) | GSK3BPOLB | |
| SCHEMBL10406650 | 0.70 | TBXAS1 (0.52) | SLC6A1PTGS1PDE4A | |
| SCHEMBL10406649 | 0.70 | TBXAS1 (0.52) | SLC6A1PTGS1PDE4A | |
| SCHEMBL6129997 | 0.69 | GSK3B (0.69) | GSK3BPOLB | |
| SCHEMBL7925528 | 0.69 | GSK3B (0.41) | GSK3BPOLB | |
| SCHEMBL24577691 | 0.69 | GSK3B (0.52) | GSK3BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109783-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD Berolina Drug Development AB (SE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014064-A2 | GABA UPTAKE INHIBITORS HAVING A PYRROLIDINE STRUCTURE | BDD BEROLINA DRUG DEVELOPMENT AB (SE) | 2000-03-16 | — | — | WO | disclosed |