Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.47 |
| ▸ | NPY4R | P50391 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | NPY1R | P25929 | 3/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592847 | 0.90 | NMT1 (0.50) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL7359195 | 0.88 | ECE1 (0.44) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL7360675 | 0.88 | NOD1 (0.55) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL7359768 | 0.86 | ECE1 (0.49) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL7363492 | 0.85 | NPY4R (0.42) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL26421505 | 0.84 | PLA2G10 (0.49) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL26429485 | 0.84 | PLA2G10 (0.49) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL7366677 | 0.83 | NPY4R (0.43) | ECE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30496935 | 0.83 | PLA2G2A (0.53) | ECE1PLA2G10NOD1 | |
| SCHEMBL29640394 | 0.83 | PLA2G2A (0.53) | ECE1PLA2G10NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |