Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.36 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360675 | 0.85 | NOD1 (0.55) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL7363053 | 0.85 | ECE1 (0.47) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL10592847 | 0.80 | NMT1 (0.50) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL7359195 | 0.79 | ECE1 (0.44) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL7366677 | 0.79 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL7359768 | 0.77 | ECE1 (0.49) | NPY4RNPY5RNPY1RNPY2RECE1 | |
| SCHEMBL29640393 | 0.77 | PLA2G2A (0.53) | ECE1NOD1PLA2G10 | |
| SCHEMBL29640394 | 0.77 | PLA2G2A (0.53) | ECE1NOD1PLA2G10 | |
| SCHEMBL30496935 | 0.77 | PLA2G2A (0.53) | ECE1NOD1PLA2G10 | |
| SCHEMBL30496966 | 0.77 | PLA2G2A (0.53) | ECE1NOD1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |