Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368669 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9ARECQLL3MBTL1 | |
| SCHEMBL6005029 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTRAB9ARECQL | |
| SCHEMBL7395815 | 0.80 | L3MBTL1 (0.43) | ALDH1A1MEN1KMT2AKCNA3MAPT | |
| SCHEMBL6539340 | 0.80 | CYP11B1 (0.45) | RAB9AHTR1ADRD2 | |
| SCHEMBL9617077 | 0.80 | KCNA3 (0.67) | ALDH1A1MEN1KMT2AKCNA3MAPT | |
| SCHEMBL910513 | 0.79 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL10458170 | 0.79 | KDM4E (0.41) | ALDH1A1MAPTRAB9ARECQLL3MBTL1 | |
| SCHEMBL11176095 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTRAB9ARECQL | |
| SCHEMBL6539635 | 0.79 | IDO1 (0.47) | KMT2ARAB9APKMRECQLLMNA | |
| SCHEMBL7284807 | 0.79 | LMNA (0.60) | ALDH1A1MEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |