Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910513 | 0.83 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL195415 | 0.81 | CYP1A2 (0.55) | SMN1; SMN2HPGDMAPTL3MBTL1NPSR1 | |
| SCHEMBL7363062 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL828475 | 0.81 | AR (0.53) | ALDH1A1SMN1; SMN2HPGDARMAPT | |
| SCHEMBL6005029 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL2244225 | 0.80 | CYP3A4 (0.51) | ALDH1A1HPGDMAPTL3MBTL1NPSR1 | |
| SCHEMBL2974587 | 0.80 | MAPT (0.56) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL11176095 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL10458170 | 0.79 | KDM4E (0.41) | ALDH1A1SMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL2118989 | 0.79 | LMNA (0.54) | ALDH1A1HPGDHTTMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |