Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1583592 | 0.76 | MEN1 (0.39) | HRH3HRH4 | |
| SCHEMBL7967646 | 0.74 | TAAR1 (0.46) | HRH3HRH4HRH1 | |
| Trifluoroacetic Acid SCHEMBL1177066 | 0.74 | HRH4 (0.34) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL1583669 | 0.73 | HRH4 (0.36) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL28710666 | 0.73 | PKM (0.37) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL28429222 | 0.71 | PIM1 (0.38) | HRH4 | |
| Trifluoroacetic Acid SCHEMBL28691408 | 0.71 | PKM (0.34) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL1206539 | 0.70 | HRH4 (0.37) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL71716 | 0.70 | HRH4 (0.37) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL2352665 | 0.70 | P2RX7 (0.39) | HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032590-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-06-08 | — | — | WO | disclosed |