SCHEMBL7363412

SCHEMBL7363412

CS(=O)(=O)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
ALOX15 P16050 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
PTGDR2 Q9Y5Y4 4/20 0.54
FFAR1 O14842 1/20 0.51
TSHR P16473 1/20 0.51
NR4A1 P22736 1/20 0.51
APEX1 P27695 1/20 0.51
IDO1 P14902 1/20 0.51
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
PTPN7 P35236 1/20 0.50
KMT2A Q03164 1/20 0.50
PTPN12 Q05209 1/20 0.50
GAA P10253 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9190264 0.91 ALDH1A1 (0.61) ALDH1A1ALOX15SMN1; SMN2PTGDR2FFAR1
SCHEMBL3370973 0.85 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL10339161 0.85 ALDH1A1 (1.00) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR
SCHEMBL11753256 0.83 ALDH1A1 (0.76) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR
SCHEMBL2931027 0.82 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2TSHRMAPTGAA
SCHEMBL339492 0.82 ALOX15 (0.81) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR
SCHEMBL1040366 0.81 ALDH1A1 (0.73) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR
SCHEMBL1040365 0.81 ALDH1A1 (0.73) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR
SCHEMBL3576066 0.81 ALDH1A1 (0.73) ALDH1A1ALOX15TSHRMEN1KMT2A
SCHEMBL5316483 0.81 ALDH1A1 (0.73) ALDH1A1ALOX15SMN1; SMN2FFAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 US disclosed
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230259028-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS NISSAN CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
US-20230259028-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS NISSAN CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
CN-110143932-A Piperazinone derivs and preparation method thereof, inhibitor and the method for preventing and treating root parasitism weeds 南开大学 2019-08-20 CN disclosed
US-9910354-B2 Resist underlayer film-forming composition and method for forming resist pattern using the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-06 US disclosed
US-9910354-B2 Resist underlayer film-forming composition and method for forming resist pattern using the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-06 US disclosed
US-20170045820-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-02-16 US disclosed
US-20170045820-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-02-16 US disclosed
EP-0781126-B1 DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM ZAMBON SPA (IT) 2001-12-12 EP disclosed
US-5674909-A FOR TREATMENT OF CARDIOVASCULAR DISORDERS ZAMBON GROUP (IT) 1997-10-07 US disclosed
EP-0781126-A2 DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM ZAMBON GROUP S.p.A. (IT) 1997-07-02 EP disclosed
WO-1996008228-A2 DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM ZAMBON GROUP S.P.A. (IT) 1996-03-21 WO disclosed