Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389364 | 0.85 | ALDH1A1 (0.53) | ALDH1A1IDO1MEN1KMT2AGAA | |
| SCHEMBL10339161 | 0.85 | ALDH1A1 (1.00) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| SCHEMBL32679596 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| SCHEMBL11753256 | 0.83 | ALDH1A1 (0.76) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| SCHEMBL339492 | 0.82 | ALOX15 (0.81) | ALDH1A1ALOX15SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL1040365 | 0.81 | ALDH1A1 (0.73) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| SCHEMBL3576066 | 0.81 | ALDH1A1 (0.73) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL7363412 | 0.81 | ALDH1A1 (0.73) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| SCHEMBL5316483 | 0.81 | ALDH1A1 (0.73) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 | |
| Lithium Ion SCHEMBL32679595 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ALOX15SMN1; SMN2FFAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318176-B1 | Color enhancement for resin blends | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-01-26 | — | — | EP | disclosed |
| EP-1299582-B1 | A PROCESS TO PREPARE MELT-COLORED POLYMERIC FIBERS | SABIC INNOVATIVE PLASTICS IP (NL) | 2008-10-08 | — | — | EP | disclosed |
| US-20030146536-A1 | Color enhancement for resin blends | GENERAL ELECTRIC COMPANY | 2003-08-07 | — | — | US | disclosed |
| US-20030129398-A1 | Process to prepare polymeric fibers with improved color and appearance | GENERAL ELECTRIC COMPANY | 2003-07-10 | — | — | US | disclosed |
| EP-1318176-A1 | Color enhancement for resin blends | GENERAL ELECTRIC COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6495079-B1 | MELT BLENDING POLYAMIDE OR POLYESTER RESIN, COLORANT AND WATER INSOLUBLE ALKYLENE ARYL POLYESTER SULFONATE SALT COPOLYMER HAVING METAL SULFONATE UNITS, FORMING INTO FILAMENTS, DRAWING INTO FIBERS HAVING IMPROVED COLOR STRENGTH | PRISMA FIBERS, INC. | 2002-12-17 | — | — | US | disclosed |