SCHEMBL9190264

SCHEMBL9190264

CS(=O)(=O)c1ccc(C=Cc2ccc(OCC(=O)O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
FFAR1 O14842 1/20 0.54
PPARG P37231 1/20 0.54
PPARD Q03181 1/20 0.54
PPARA Q07869 1/20 0.54
AKR1C3 P42330 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
PTGS2 P35354 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
ALOX15 P16050 1/20 0.47
PTGDR2 Q9Y5Y4 2/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NR1I2 O75469 1/20 0.46
LMNA P02545 1/20 0.46
PGR P06401 1/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7363412 0.91 ALDH1A1 (0.73) ALDH1A1FFAR1MEN1KMT2ASMN1; SMN2
SCHEMBL20024689 0.85 ALOX15 (0.63) ALDH1A1FFAR1PPARGPPARDPPARA
SCHEMBL9193694 0.84 NPSR1 (0.69) ALDH1A1PTGS2SMN1; SMN2ALOX15GAA
SCHEMBL6697095 0.80 ALOX15 (0.68) ALDH1A1FFAR1PPARGPPARDPPARA
SCHEMBL6697101 0.80 ALOX15 (0.68) ALDH1A1FFAR1PPARGPPARDPPARA
SCHEMBL9681054 0.80 PTPN1 (0.47) PPARAPTGS2SMN1; SMN2NR1I2
SCHEMBL9681048 0.80 PTPN1 (0.47) PPARAPTGS2SMN1; SMN2NR1I2
SCHEMBL20024742 0.79 ALOX15 (0.55) ALDH1A1FFAR1PPARGPPARDPPARA
SCHEMBL14314453 0.79 POLB (0.59) ALDH1A1FFAR1PPARGPPARDPPARA
SCHEMBL3362007 0.79 PPARG (0.81) FFAR1PPARGPPARDPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498184-B1 Organic nonlinear optical material MITSUBISHI CHEM CORP (JP) 1995-10-18 EP disclosed
US-5194511-A Optical recording material, films and sheets MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-03-16 US disclosed
EP-0498184-A2 Organic nonlinear optical material MITSUBISHI CHEMICAL CORPORATION (JP) 1992-08-12 EP disclosed