Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557226 | 0.78 | — | — | |
| SCHEMBL28291358 | 0.74 | GNAI3 (0.40) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL4594886 | 0.74 | GNAI3 (0.38) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL23146698 | 0.74 | — | — | |
| SCHEMBL4437499 | 0.72 | GNAI3 (0.42) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL24045737 | 0.72 | HSD11B1 (0.33) | — | |
| SCHEMBL24011271 | 0.72 | PHGDH (0.32) | — | |
| SCHEMBL3317716 | 0.71 | CXCR4 (0.32) | — | |
| SCHEMBL28289844 | 0.71 | GNAI3 (0.38) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL6864465 | 0.70 | GPR119 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756519-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0800395-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0800395-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019222-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |