Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289844 | 0.92 | GNAI3 (0.38) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL27947183 | 0.86 | CHRNB2 (0.36) | GPR119CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL4594886 | 0.85 | GNAI3 (0.38) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL27473154 | 0.83 | SIGMAR1 (0.35) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL27722912 | 0.83 | GNAO1 (0.46) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL27702404 | 0.82 | GNAO1 (0.48) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL27694570 | 0.82 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1CHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL27722005 | 0.82 | HPGD (0.37) | GNAI3GNAO1GNAI1CHRNB2CHRNA3 | |
| Hydrochloric Acid SCHEMBL7098403 | 0.82 | HPGD (0.37) | GNAI3GNAO1GNAI1CHRNB2CHRNA3 | |
| SCHEMBL28800368 | 0.81 | CHRNB2 (0.50) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |