Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363496 | 1.00 | TAAR1 (0.59) | TAAR1ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL7365622 | 1.00 | TAAR1 (0.59) | TAAR1ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL7365324 | 0.78 | MME (0.66) | PIN1MEN1CYP1A2KMT2ACTRB1 | |
| SCHEMBL7443024 | 0.76 | PIN1 (0.49) | PIN1MEN1CYP1A2KMT2ACTRB1 | |
| SCHEMBL7363566 | 0.76 | PIN1 (0.59) | PIN1MEN1CYP1A2KMT2ACTRB1 | |
| SCHEMBL7370588 | 0.76 | MME (0.59) | — | |
| SCHEMBL7367862 | 0.75 | MME (0.54) | ALDH1A1PIN1MEN1CYP1A2KMT2A | |
| SCHEMBL7367157 | 0.75 | NAALAD2 (0.58) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7367162 | 0.75 | NAALAD2 (0.58) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10537718 | 0.75 | TAAR1 (0.68) | TAAR1ALDH1A1LMNACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |