Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.66 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370588 | 0.88 | MME (0.59) | MMEACE | |
| SCHEMBL7443024 | 0.82 | PIN1 (0.49) | MMEMEN1CYP1A2KMT2APIN1 | |
| SCHEMBL7367862 | 0.81 | MME (0.54) | MMEACEMEN1CYP1A2KMT2A | |
| SCHEMBL7369309 | 0.81 | MME (0.72) | MMEACE | |
| SCHEMBL9068996 | 0.81 | MME (0.73) | MMEACEKMT2A | |
| SCHEMBL7363022 | 0.80 | CTRB1 (0.52) | MMEMEN1CYP1A2KMT2APIN1 | |
| SCHEMBL4325212 | 0.80 | MME (1.00) | MMEACECTRB1 | |
| SCHEMBL4325217 | 0.80 | MME (1.00) | MMEACECTRB1 | |
| SCHEMBL7363566 | 0.79 | PIN1 (0.59) | ACEMEN1CYP1A2KMT2APIN1 | |
| SCHEMBL7366443 | 0.79 | MME (0.51) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |