Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370638 | 0.90 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL7370619 | 0.89 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL7368874 | 0.85 | FOLH1 (0.53) | SMN1; SMN2 | |
| SCHEMBL10799156 | 0.82 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4ENPSR1 | |
| Ethyl Benzoate SCHEMBL10799177 | 0.81 | KMT2A (0.48) | RAB9ASMN1; SMN2NPC1GAAMEN1 | |
| SCHEMBL7433755 | 0.81 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL7384102 | 0.81 | MAPT (0.56) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL28753025 | 0.80 | MAPT (0.60) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL19805597 | 0.80 | MAPT (0.60) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL28753021 | 0.80 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |