Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715677 | 0.86 | KMT2A (0.39) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2444857 | 0.68 | KMT2A (0.47) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7363683 | 0.68 | KMT2A (0.40) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16858007 | 0.67 | KMT2A (0.46) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10482591 | 0.66 | KMT2A (0.37) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3876432 | 0.65 | KMT2A (0.47) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL21874427 | 0.65 | KMT2A (0.43) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27833672 | 0.64 | LMNA (0.38) | TSHRALDH1A1FDPS | |
| SCHEMBL3081571 | 0.63 | ALDH1A1 (0.50) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL14220661 | 0.63 | ALDH1A1 (0.37) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307090-B1 | OXALYL ENDCAPPED; CONTAINING A BIVALENT RADICAL OF PHOSPHOTYROSINE OR A PHOSPHOTYROSINE MIMETIC | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-10-23 | — | — | US | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |