Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363687 | 0.86 | MEN1 (0.40) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL10482591 | 0.68 | KMT2A (0.37) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL3876432 | 0.67 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL28701694 | 0.65 | KMT2A (0.44) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL2444857 | 0.64 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL17260384 | 0.64 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL28175766 | 0.64 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL7363683 | 0.64 | KMT2A (0.40) | KMT2ASMN1; SMN2MEN1CYP2C9CYP2C19 | |
| SCHEMBL27833672 | 0.63 | LMNA (0.38) | ALDH1A1LMNATSHRFDPS | |
| Phosphoric Acid SCHEMBL1242659 | 0.62 | ALDH1A1 (0.50) | KMT2AMEN1CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007913-A1 | PEPTIDE ANTAGONISTS OF SH2 BINDING AND THERAPEUTIC USES THEREOF | WARNER-LAMBERT COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |