Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567689 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL29559790 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL220780 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL56335 | 0.81 | CA2 (0.48) | ALDH1A1CYP3A4TDP1TSHRPOLB | |
| SCHEMBL17729353 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL22146862 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL27701508 | 0.78 | APP (0.60) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL11593518 | 0.78 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL2123029 | 0.78 | AR (0.44) | ALDH1A1CYP3A4TDP1GAAHPGD | |
| SCHEMBL5125769 | 0.76 | LMNA (0.40) | ALDH1A1CYP3A4TDP1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100339442-C | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2007-09-26 | — | — | CN | claimed |
| CN-1563202-A | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2005-01-12 | — | — | CN | claimed |
| EP-3099694-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015113451-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-08-06 | — | — | WO | disclosed |
| CN-100339442-C | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2007-09-26 | — | — | CN | disclosed |
| CN-1563202-A | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2005-01-12 | — | — | CN | disclosed |
| WO-1998050030-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |
| WO-1997007131-A1 | ACYLATED OLIGOPEPTIDES CONTAINING PHOSPHOTYROSINE AS INHIBITORS OF PROTEIN TYROSINE KINASES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |