Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197396 | 0.85 | MAPK1 (0.49) | TSHRMAPK1PDE4AGAA | |
| SCHEMBL3662959 | 0.85 | ALDH1A1 (0.43) | ACHETSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2702025 | 0.85 | MAPT (0.54) | TSHRALDH1A1MAPK1HPGDPDE4A | |
| SCHEMBL16641175 | 0.83 | CA2 (0.54) | CA2CA12CA1CA7CA9 | |
| SCHEMBL10669643 | 0.83 | TSHR (0.58) | TSHRALDH1A1NR3C1GAA | |
| SCHEMBL6210745 | 0.83 | AR (0.40) | ACHETSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11673151 | 0.83 | ALDH1A1 (0.40) | CA2CA12CA1CA7CA9 | |
| SCHEMBL11593518 | 0.83 | ALDH1A1 (0.39) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2123029 | 0.83 | AR (0.44) | ACHEALDH1A1CYP3A4ARHPGD | |
| SCHEMBL9528325 | 0.82 | FDPS (0.50) | ALDH1A1CYP2C9CYP2C19POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 680 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227036-B | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-11 | — | — | CN | claimed |
| EP-3904330-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | Academy Of Military Medical Sciences (CN) | 2021-11-03 | — | — | EP | claimed |
| CN-113227036-A | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-08-06 | — | — | CN | claimed |
| US-11077116-B2 | Isoxazole derivatives as inducers of fetal hemoglobin in erythroid precursor cells from beta-thalassemic patients | RARE PARTNERS SRL (IT) | 2021-08-03 | — | — | US | claimed |
| US-20210130315-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-06 | — | — | US | claimed |
| CN-111757880-A | Method for synthesizing cyclic depsipeptides | 拜耳动物保健有限责任公司 | 2020-10-09 | — | — | CN | claimed |
| EP-3676265-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | Bayer Animal Health GmbH (DE) | 2020-07-08 | — | — | EP | claimed |
| US-20200206234-A1 | ISOXAZOLE DERIVATIVES AS INDUCERS OF FETAL HEMOGLOBIN IN ERYTHROID PRECURSOR CELLS FROM BETA-THALASSEMIC PATIENTS | RARE PARTNERS SRL (IT) | 2020-07-02 | — | — | US | claimed |
| WO-2020135569-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-07-02 | — | — | WO | claimed |
| CN-107759429-B | Method for synthesizing chiral pyrimidine acyclic nucleoside containing sulfur side chain through conjugate addition-protonation reaction | 河南师范大学 | 2020-06-16 | — | — | CN | claimed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| EP-0259268-A1 | Process for the preparation of optically active beta-lactams | CIBA-GEIGY AG (CH) | 1988-03-09 | — | — | EP | claimed |
| EP-0257102-A1 | AGENTS FOR TREATING NEUROPHATHY | Mitsui Chemicals, Inc. (JP) | 1988-03-02 | — | — | EP | claimed |
| US-4661512-A | Adamantanamine derivatives, processes for their preparation and drugs in which they are present | S. A. PANMEDICA (FR) | 1987-04-28 | — | — | US | claimed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | claimed |
| EP-0075629-A1 | Imidazole derivatives, their preparation, and their pharmaceutical compositions | Sumitomo Chemical Industries Ltd. (JP) | 1983-04-06 | — | — | EP | claimed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| US-4010193-A | (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1977-03-01 | — | — | US | claimed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130315-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | DNPEP, NPEPPS, PREP | CA2 3070/4885CA12 565/4885CA1 2176/4885 |
| US-11077116-B2 | Isoxazole derivatives as inducers of fetal hemoglobin in erythroid precursor cells from beta-thalassemic patients | HBZ, HBB, HBG2 | CA2 1098/4885CA12 2661/4885CA1 3309/4885 |
| US-20200206234-A1 | ISOXAZOLE DERIVATIVES AS INDUCERS OF FETAL HEMOGLOBIN IN ERYTHROID PRECURSOR CELLS FROM BETA-THALASSEMIC PATIENTS | HBZ, HBB, HBG2 | CA2 1098/4885CA12 2661/4885CA1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.