Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364292 | 0.88 | KCNH2 (0.53) | KCNJ1KCNH2ALDH1A1VCAM1LOXL2 | |
| SCHEMBL7363755 | 0.85 | KCNJ1 (0.54) | KCNJ1KCNH2FOLH1GLAVCAM1 | |
| SCHEMBL7363757 | 0.76 | KCNJ1 (0.51) | KCNJ1KCNH2VCAM1LOXL2P4HB | |
| SCHEMBL7365383 | 0.75 | KCNJ1 (0.57) | KCNJ1KCNH2ALDH1A1GLAP4HB | |
| SCHEMBL7365988 | 0.73 | KCNH2 (0.45) | KCNJ1KCNH2ALDH1A1FOLH1KMT2A | |
| SCHEMBL7453828 | 0.73 | KCNJ1 (0.60) | KCNJ1KCNH2ALDH1A1MAPTKMT2A | |
| SCHEMBL27524576 | 0.72 | SIGMAR1 (0.49) | KCNJ1KCNH2ALDH1A1LOXL2SIGMAR1 | |
| SCHEMBL28865565 | 0.70 | HTR2B (0.50) | KCNJ1KCNH2HTR2BALDH1A1FOLH1 | |
| SCHEMBL28248372 | 0.70 | HTR2B (0.54) | KCNJ1KCNH2HTR2BALDH1A1FOLH1 | |
| SCHEMBL6690598 | 0.69 | LOXL2 (0.52) | ALDH1A1LOXL2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |