Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035718 | 0.88 | GPR119 (0.65) | GPR119TGFBR1DDB1CRBN | |
| SCHEMBL31753740 | 0.88 | GPR119 (0.59) | GPR119 | |
| SCHEMBL31753269 | 0.88 | GPR119 (0.72) | GPR119 | |
| SCHEMBL4516831 | 0.88 | GPR119 (0.74) | GPR119 | |
| SCHEMBL7365948 | 0.85 | YAP1 (0.56) | GPR119 | |
| SCHEMBL8473896 | 0.84 | GPR119 (0.79) | GPR119TGFBR1 | |
| SCHEMBL7362766 | 0.84 | GPR119 (0.79) | GPR119TGFBR1 | |
| SCHEMBL7364852 | 0.84 | GPR119 (0.51) | GPR119 | |
| SCHEMBL15441763 | 0.83 | GPR119 (0.81) | GPR119 | |
| SCHEMBL20076213 | 0.83 | GPR119 (0.54) | GPR119TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |