Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA5A | P35218 | 6/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362007 | 0.95 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| Sarcosine SCHEMBL7364548 | 0.83 | ITGB3 (0.50) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| Arginine SCHEMBL7360830 | 0.83 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL18118973 | 0.80 | ALDH1A1 (0.72) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL27566680 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL16503505 | 0.78 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL24146497 | 0.78 | ALDH1A1 (0.66) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL27656329 | 0.77 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL25434270 | 0.77 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19CA1CA2 | |
| SCHEMBL27792104 | 0.77 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025472-A | PEPTIDE ALDEHYDES WHICH ARE POTENT INHIBITORS OF FACTOR XA, USEFUL AS THERAPEUTIC AGENTS FOR DISEASE STATES IN MAMMALS CHARACTERIZED BY ABNORMAL THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5696231-A | ANTICOAGULANTS; CARDIOVASCULAR DISORDERS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996019493-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |