Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372331 | 0.89 | POLB (0.56) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL10968562 | 0.85 | POLB (0.59) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL7365119 | 0.83 | KDM4E (0.56) | ABCB1LMNACYP1A2SLC22A1KCNK2 | |
| SCHEMBL1330304 | 0.81 | POLB (0.62) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL7363653 | 0.81 | KDM4E (0.70) | ADRB2ADRB1ADRB3KMT2AKDM4E | |
| SCHEMBL7368728 | 0.78 | L3MBTL1 (0.53) | POLBADRB2ADRB1ADRB3KCNH2 | |
| SCHEMBL7363467 | 0.78 | ADRB1 (0.62) | CYP1A2ADRB2ADRB1ADRB3HTR2B | |
| SCHEMBL7367538 | 0.77 | MEN1 (0.62) | LMNACYP1A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL7364771 | 0.77 | MEN1 (0.62) | LMNACYP1A2CYP2D6ADRB2ADRB1 | |
| SCHEMBL7367855 | 0.76 | MEN1 (0.63) | LMNACYP1A2CYP2D6ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |