Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365119 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1KMT2AHTR1AHTR7 | |
| SCHEMBL7363467 | 0.81 | ADRB1 (0.62) | KDM4EKMT2AHTR1AADRB1ADRB2 | |
| SCHEMBL7367538 | 0.81 | MEN1 (0.62) | KMT2AADRB1ADRB2ADRB3 | |
| SCHEMBL7364771 | 0.81 | MEN1 (0.62) | KMT2AADRB1ADRB2ADRB3 | |
| SCHEMBL7363941 | 0.81 | POLB (0.55) | KDM4EALDH1A1KMT2AADRB1ADRB2 | |
| SCHEMBL7368728 | 0.80 | L3MBTL1 (0.53) | KDM4EALDH1A1KMT2AADRB1ADRB2 | |
| SCHEMBL7367855 | 0.80 | MEN1 (0.63) | KMT2AADRB1ADRB2ADRB3 | |
| SCHEMBL7367227 | 0.76 | HTR1A (0.61) | KDM4EALDH1A1KMT2AHTR1AADRB1 | |
| SCHEMBL6690111 | 0.75 | MEN1 (0.65) | KMT2AADRB1ADRB2ADRB3 | |
| SCHEMBL11798041 | 0.74 | ADRB1 (0.65) | KDM4EKMT2AHTR1AADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |