Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364029 | 0.85 | SYK (0.51) | SYKCTSLCTSBCTSSMAPT | |
| SCHEMBL7412656 | 0.82 | L3MBTL1 (0.39) | SYKCTSLCTSBCTSSCTSK | |
| SCHEMBL7303613 | 0.79 | AKT1 (0.38) | CTSLCTSBCTSSCTSKATM | |
| SCHEMBL7496391 | 0.79 | SYK (0.60) | SYKCTSLCTSBCTSSMAPT | |
| SCHEMBL7497040 | 0.78 | SYK (0.59) | SYKCTSLCTSBCTSSMAPT | |
| SCHEMBL9337020 | 0.75 | CTSL (0.43) | CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL7575645 | 0.74 | SYK (0.55) | SYKCTSLCTSBCTSSMAPT | |
| SCHEMBL7368347 | 0.74 | — | — | |
| SCHEMBL7571011 | 0.73 | SYK (0.54) | SYKCTSLCTSBCTSSMAPT | |
| SCHEMBL9753834 | 0.73 | MME (0.40) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |