Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 12/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753834 | 0.89 | MME (0.40) | CTSLCTSBCTSKMMEALDH1A1 | |
| SCHEMBL9753937 | 0.84 | SMN1; SMN2 (0.44) | CTSLCTSBCTSKMME | |
| SCHEMBL9337016 | 0.82 | MME (0.52) | CA1CA2MMEALDH1A1 | |
| SCHEMBL6430188 | 0.82 | MME (0.52) | CA1CA2MMEALDH1A1 | |
| SCHEMBL6429465 | 0.80 | MME (0.50) | CA1CA2MMEALDH1A1 | |
| SCHEMBL7412656 | 0.78 | L3MBTL1 (0.39) | CTSLCTSBCTSK | |
| SCHEMBL11636918 | 0.78 | CA1 (0.63) | CTSLCTSKCA1CA2ALDH1A1 | |
| SCHEMBL26825081 | 0.75 | CA1 (0.56) | CTSLCTSKCA1CA2ALDH1A1 | |
| SCHEMBL7364030 | 0.75 | SYK (0.48) | CTSLCTSBCTSKALDH1A1 | |
| Hydrochloric Acid SCHEMBL28012229 | 0.74 | CA1 (0.55) | CTSLCTSKCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362902-A | Diuretics and treatment of cardiovascular disorders | PFIZER INC. (US) | 1994-11-08 | — | — | US | disclosed |
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |
| WO-1991008195-A1 | N-(1-(2-CARBOXYETHYL)CYCLOALKYL CARBONYL)-BETA-ALANINE DERIVATIVES FOR PHARMACEUTICAL USE | PFIZER LIMITED (GB) | 1991-06-13 | — | — | WO | disclosed |