Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KYNU | Q16719 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337020 | 0.89 | CTSL (0.43) | MMECTSBCTSLCTSKALDH1A1 | |
| SCHEMBL5925056 | 0.83 | MME (0.49) | MMECTSBCTSLALDH1A1CTSS | |
| SCHEMBL9753833 | 0.83 | MME (0.49) | MMECTSBCTSLALDH1A1CTSS | |
| SCHEMBL5796118 | 0.82 | MME (0.48) | MMECTSBCTSLALDH1A1CTSS | |
| SCHEMBL6277456 | 0.81 | MME (0.33) | MMECTSBCTSLCTSK | |
| SCHEMBL7412656 | 0.81 | L3MBTL1 (0.39) | CTSBCTSLCTSKCTSSCYP2C19 | |
| SCHEMBL9753937 | 0.80 | SMN1; SMN2 (0.44) | MMECTSBCTSLCTSK | |
| SCHEMBL5702727 | 0.78 | MME (0.33) | MME | |
| SCHEMBL6804184 | 0.77 | MME (0.46) | MMEALDH1A1 | |
| SCHEMBL6804195 | 0.77 | MME (0.46) | MMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |