SCHEMBL7364063

SCHEMBL7364063

CC(C)C[C@H](NC(=O)P(=O)(O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 3/20 0.70
ALDH1A1 P00352 2/20 0.60
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 1/20 0.53
MMP1 P03956 4/20 0.52
MMP2 P08253 3/20 0.52
MMP8 P22894 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
MMP9 P14780 1/20 0.52
FOLH1 Q04609 5/20 0.50
MMP3 P08254 1/20 0.50
GRN P28799 3/20 0.49
SORT1 Q99523 3/20 0.49
NAALAD2 Q9Y3Q0 2/20 0.46
PLA2G2A P14555 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7366642 0.78 LAP3 (0.56) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL28824274 0.77 ALDH1A1 (0.72) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL13838843 0.77 ALDH1A1 (0.72) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL13785341 0.77 ALDH1A1 (0.72) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL15302480 0.77 ALDH1A1 (0.72) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL28214706 0.77 ALDH1A1 (0.88) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL14503214 0.77 LAP3 (0.55) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL3447885 0.76 ALDH1A1 (0.64) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL628967 0.76 ALDH1A1 (0.64) LAP3ALDH1A1MEN1LMNAKMT2A
SCHEMBL628966 0.76 ALDH1A1 (0.64) LAP3ALDH1A1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1223945-A1 COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2002-07-24 EP claimed
WO-2001026661-A1 COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2001-04-19 WO claimed