Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRN | P28799 | 2/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886634 | 0.78 | FPR2 (0.39) | LAP3CA12CA1CA2CA9 | |
| SCHEMBL7364063 | 0.78 | LAP3 (0.70) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9505346 | 0.74 | FPR2 (0.46) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7376495 | 0.74 | ALDH1A1 (0.43) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7376499 | 0.74 | ALDH1A1 (0.43) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3090822 | 0.74 | FPR2 (0.46) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9830039 | 0.73 | ALDH1A1 (0.58) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL729840 | 0.73 | ALDH1A1 (0.58) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9557207 | 0.73 | ALDH1A1 (0.58) | LAP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7376049 | 0.72 | ALDH1A1 (0.41) | LAP3ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223945-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001026661-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-04-19 | — | — | WO | disclosed |