Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 3/20 | 0.52 |
| ▸ | CA5A | P35218 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939916 | 0.80 | TBXA2R (0.66) | CA12CA1CA2CA3CA6 | |
| SCHEMBL7367863 | 0.80 | TBXA2R (0.66) | CA12CA1CA2CA3CA6 | |
| SCHEMBL6945457 | 0.79 | TBXA2R (0.67) | CA12CA1CA2CA3CA6 | |
| SCHEMBL6946805 | 0.77 | NPC1 (0.47) | CA12CA1CA2CA3CA6 | |
| SCHEMBL7631740 | 0.77 | MGLL (0.52) | MGLLTBXA2RNAAA | |
| SCHEMBL6945540 | 0.77 | YAP1 (0.59) | EPHX1 | |
| SCHEMBL7367027 | 0.76 | TBXA2R (0.61) | CA12CA1CA2CA3CA6 | |
| SCHEMBL29617529 | 0.75 | CA2 (0.70) | CA12CA1CA2CA3CA6 | |
| SCHEMBL15638342 | 0.75 | HCAR3 (0.46) | CA12CA1CA2CA3CA6 | |
| SCHEMBL15635836 | 0.74 | YAP1 (0.56) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |